Restoring Metabolic and Reproductive Health With Sleep in PCOS Study, CPAP Trial
In this study, the researchers are trying to learn more about the relationship between Polycystic Ovary Syndrome and Obstructive Sleep Apnea (OSA). Obstructive Sleep Apnea is a sleep-related breathing disorder that involves a decrease or complete stop in airflow. The purpose of this study is to find out why some people with obstructive sleep apnea have higher levels of insulin resistance, and the investigators will study the role of hypoxia (low levels of oxygen in the blood at night) in insulin resistance and see if insulin resistance improves during your treatment with CPAP.
• Subjects found to have moderate to severe OSA (AHI \>15)
• PCOS diagnosis satisfies both the hyperandrogenic and oligo-ovulatory requirements of Rotterdam criteria
• Ages 18-40
• BMI 25-45 kg/m2
• Fasting insulin \>16
• At-risk score on Berlin Questionnaire